Matthias Gehringer: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure-Activity Relationship Study on Tofacitinib Bioisosteres

Gehringer, Matthias, Forster, Michael, Pfaffenrot, Ellen, Bauer, Silke M., Laufer, Stefan A.

Journal:

Year:

2014

Language:

english

File:

PDF, 703 KB

english, 2014

2

Recent Developments in JAK3 Inhibition: Isoform Selectivity by Covalent Targeting of Cys909

Forster, Michael, Gehringer, Matthias, Laufer, Stefan A.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

3

Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology

Gehringer, Matthias, Laufer, Stefan A.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 3.60 MB

english, 2018

4

Hypercube embedding heuristics: An evaluation

Woei-Kae Chen, Matthias F. M. Stallmann, Edward F. Gehringer

Journal:

International Journal of Parallel Programming

Year:

1989

Language:

english

File:

PDF, 2.16 MB

english, 1989

5

Silica-supported l-proline organocatalysts for asymmetric aldolisation

Alexandra Zamboulis, Nicolas J. Rahier, Matthias Gehringer, Xavier Cattoën, Gilles Niel, Catherine Bied, Joël J.E. Moreau, Michel Wong Chi Man

Journal:

Tetrahedron: Asymmetry

Year:

2009

Language:

english

File:

PDF, 572 KB

english, 2009

6

Design and Synthesis of Tricyclic JAK3 Inhibitors with Picomolar Affinities as Novel Molecular Probes

Gehringer, Matthias, Pfaffenrot, Ellen, Bauer, Silke, Laufer, Stefan A.

Journal:

Year:

2014

Language:

english

File:

PDF, 645 KB

english, 2014

7

A direct enzyme-linked immunosorbent assay (ELISA) for the quantitative evaluation of Janus Kinase 3 (JAK3) inhibitors

Bauer, Silke M., Gehringer, Matthias, Laufer, Stefan A.

Journal:

Analytical Methods

Year:

2014

Language:

english

File:

PDF, 603 KB

english, 2014

8

Solution-Phase Parallel Synthesis of Ruxolitinib-Derived Janus Kinase Inhibitors via Copper-Catalyzed Azide–Alkyne Cycloaddition

Gehringer, Matthias, Forster, Michael, Laufer, Stefan A.

Journal:

ACS Combinatorial Science

Year:

2015

Language:

english

File:

PDF, 822 KB

english, 2015

9

Back Cover: Design and Synthesis of Tricyclic JAK3 Inhibitors with Picomolar Affinities as Novel Molecular Probes (ChemMedChem 2/2014)

Gehringer, Matthias, Pfaffenrot, Ellen, Bauer, Silke, Laufer, Stefan A.

Journal:

Year:

2014

File:

PDF, 1.13 MB

2014

10

Inhibitors of c-Jun N-Terminal Kinases: An Update

Koch, Pierre, Gehringer, Matthias, Laufer, Stefan A.

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

11

New insights into novel inhibitors against deoxyhypusine hydroxylase from plasmodium falciparum: compounds with an iron chelating potential

von Koschitzky, Imke, Gerhardt, Heike, Lämmerhofer, Michael, Kohout, Michal, Gehringer, Matthias, Laufer, Stefan, Pink, Mario, Schmitz-Spanke, Simone, Strube, Christina, Kaiser, Annette

Journal:

Year:

2015

Language:

english

File:

PDF, 708 KB

english, 2015

12

c-Jun N -terminal kinase inhibitors: a patent review (2010 – 2014)

Gehringer, Matthias, Muth, Felix, Koch, Pierre, Laufer, Stefan A

Journal:

Expert Opinion on Therapeutic Patents

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

13

2-(3-{(3 R ,4 R )-4-Methyl-3-[methyl(7 H -pyrrolo[2,3- d ]pyrimidin-4-yl)amino]piperidin-1-yl}oxetan-3-yl)acetonitrile monohydrate

Gehringer, Matthias, Pfaffenrot, Ellen, Keck, Peter R. W. E. F., Schollmeyer, Dieter, Laufer, Stefan A.

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2014

Language:

english

File:

PDF, 250 KB

english, 2014

14

Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1)

Ostrovskyi, Dmytro, Rumpf, Tobias, Eib, Julia, Lumbroso, Alexandre, Slynko, Inna, Klaeger, Susan, Heinzlmeir, Stephanie, Forster, Michael, Gehringer, Matthias, Pfaffenrot, Ellen, Bauer, Silke Mona, Sc

Journal:

Future Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 3.23 MB

english, 2016

15

Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Forster, Michael, Chaikuad, Apirat, Bauer, Silke M., Holstein, Julia, Robers, Matthew B., Corona, Cesear R., Gehringer, Matthias, Pfaffenrot, Ellen, Ghoreschi, Kamran, Knapp, Stefan, Laufer, Stefan A.

Journal:

Cell Chemical Biology

Year:

2016

Language:

english

File:

PDF, 2.10 MB

english, 2016

16

The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR

Bieri, Raphael, Scherr, Nicole, Ruf, Marie-Thérèse, Dangy, Jean-Pierre, Gersbach, Philipp, Gehringer, Matthias, Altmann, Karl-Heinz, Pluschke, Gerd

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.45 MB

english, 2017

17

Click Chemistry: Novel Applications in Cell Biology and Drug Discovery

Gehringer, Matthias, Laufer, Stefan A.

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 651 KB

english, 2017

18

Neue Anwendungen der Klick-Chemie in Zellbiologie und Wirkstoffentwicklung

Gehringer, Matthias, Laufer, Stefan A.

Journal:

Angewandte Chemie

Year:

2017

Language:

german

File:

PDF, 579 KB

german, 2017

19

Development, Optimization and Structure–Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4-d]pyrrolo[2,3-b]pyridine Scaffold.

Forster, Michael, Chaikuad, Apirat, Dimitrov, Teodor, Döring, Eva, Holstein, Julia, Berger, Benedict-Tilman, Gehringer, Matthias, Ghoreschi, Kamran, Müller, Susanne, Knapp, Stefan, Laufer, Stefan A.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.02 MB

english, 2018

20

The chemistry and biology of mycolactones

Gehringer, Matthias, Altmann, Karl-Heinz

Journal:

Beilstein Journal of Organic Chemistry

Year:

2017

Language:

english

File:

PDF, 2.31 MB

english, 2017

21

Developing small-molecule inhibitors of HECT-type ubiquitin ligases for therapeutic applications: challenges and opportunities

Chen, Dan, Gehringer, Matthias, Lorenz, Sonja

Journal:

Year:

2018

Language:

english

File:

PDF, 3.61 MB

english, 2018

22

Configurationally Stabilized Analogs of M. ulcerans Exotoxins Mycolactones A and B Reveal the Importance of Side Chain Geometry for Mycolactone Virulence

Gehringer, Matthias, Mäder, Patrick, Gersbach, Philipp, Pfeiffer, Bernhard, Scherr, Nicole, Dangy, Jean-Pierre, Pluschke, Gerd, Altmann, Karl-Heinz

Journal:

Organic Letters

Year:

2019

Language:

english

File:

PDF, 1.13 MB

english, 2019

23

[Topics in Medicinal Chemistry] || Covalent Janus Kinase 3 Inhibitors

Gehringer, Matthias

Year:

2020

File:

PDF, 1.46 MB

2020

24

Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans

Warryn, Louisa, Dangy, Jean-Pierre, Gersbach, Philipp, Gehringer, Matthias, SchÃ¤fer, Anja, Ruf, Marie-ThÃ©rÃ¨se, Ruggli, Nicolas, Altmann, Karl-Heinz, Pluschke, Gerd, Stinear, Tim P.

Journal:

PLoS Neglected Tropical Diseases

Year:

2020

File:

PDF, 2.57 MB

2020

25

[Topics in Medicinal Chemistry] || Covalent Kinase Inhibitors: An Overview

Gehringer, Matthias

Year:

2020

File:

PDF, 2.54 MB

2020

26

Covalent inhibitors: back on track?

Gehringer, Matthias

Journal:

Future Medicinal Chemistry

Year:

2020

File:

PDF, 218 KB

2020

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски